The first book starts off with a pretty good opening line: "I'd been waiting for the vampire for years when he walked into the bar." Immediately from there, it launches into the story of Sookie Stackhouse, a Southern small-town waitress with two disabilities: the curse of having to read peoples' minds, and a really stupid name. The first one is what first draws her to the vampire, because she can't read his mind, which she thinks is awesome because men are scum and they only think terrible things. And although not mentioned, the stupid name problem probably helps her to relate to Bill, which is a pretty dumb name for a vampire. After she meets him, people start dying, hell breaks loose, etc etc. You know the drill.
But let's just pretend it's (1) and focus on the positive. Partly because of the informal first-person style, Sookie's personality comes through, and the little expressions she uses and social conventions she frets over help to bring the Southern setting to life. I could've done without her agonizing over what to wear in every single chapter and the sickening mind-games she casually manipulates the males in her life with, but intentional or not, she at least seems like a flawed, real (albeit stereotypically female) person.
There is a murder mystery that ties each chapter together, but the characters seem more interested in short-term questions about cleaning the house, work timetables, and vampire ejaculation than about who's killing their friends and families. Some chapters can feel separated from the rest of the story, as if nobody remembers what came before. As a single book it's disjointed, and actually feels a bit like a big pilot episode, with dangling plot elements that exist only to set up future installments. But since there are plenty of future installments, and there is a TV series based on it, this episodic storytelling isn't entirely unwelcome.
The novel departs from the first season of True Blood in quite a few significant ways. Most obvious is the complete lack of Tara in the novel, the alternate reason for Bill's little trip late in the book, and the ending. There is also one plot element missing from the show, which is a great thing because, while I hate to use this word, it can only be described as retarded. Without giving anything away, it starts with "B"; anyone who's read it will know what I'm talking about. True Blood also added a few entirely new subplots that I thought worked as well, if not better, than what was from the novel. This gives me hope for the show, because many of the show's flaws were inherited from the book, and the creators' willingness to depart from it can only bode well for future seasons.
Perhaps I've been a bit snarky in describing Dead Until Dark, but I did enjoy it quite a bit. It's not a masterfully told story, but it does a few new things with the crowded vampire genre, and has just enough sex and violence to provide some cheap thrills. I recommend it for fans of the show looking to see what inspired it, or anyone else who likes cheesy vampire crap.